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	Provedor de dados Nature Precedings (1) Autor Donald C. Cooper (1) Samuel Dolzani (1) Palavra-chave Neuroscience (1) Pharmacology (1) Tipo do documento Manuscript (1) Ano 2012 (1) País United Kingdom (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última A novel apparatus/protocol designed for optogenetic manipulation and recording of individual neurons during a motivation and working memory task in the rodent Nature Precedings Samuel Dolzani; Donald C. Cooper. Innovative molecular tools allow neuroscientists to study neural circuitry associated with specific behaviors. Consequently, behavioral methods must be developed to interface with these new molecular tools in order for neuroscientists to identify the causal elements underlying behavior and decision-making processes. Here we present an apparatus and protocol for a novel Go/No-Go behavioral paradigm to study the brain attention and motivation/reward circuitry in awake, head-restrained rodents. This experimental setup allows: (1) Painless and stable restraint of the head and body; (2) Rapid acquisition to simple or complex operant tasks; (3) Repeated electrophysiological single and multiple unit recordings during ongoing behavior; (4) Pharmacological and... Tipo: Manuscript Palavras-chave: Neuroscience; Pharmacology. Ano: 2012 URL: http://precedings.nature.com/documents/7152/version/1 Registros recuperados: 1 Primeira ... 1 ... Última

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